Decoding the threats to our bodies

Antibiotics have saved many lives in the last 80 years and are the basis of modern medicine. However, antimicrobial resistance is posing an increasing threat to the health of the world population. My talk will explain, where resistance comes from, and summarize the current situation and prognoses for the next decades in a One Health and Global Health context. Following a brief overview on measures to reduce antibiotic prescriptions, an overview on innovative treatment options for bacterial infections will be given. Finally, I will discuss the challenges of the business case for antibiotics.

All of us experience daily rhythms of sleep and wakefulness, eating and fasting, resting and activity, synchronized to the Earth's rotation and light/darkness. These daily cycles are controlled by our brains, hormones and cellular machineries called transcription factors. In turn these control the 24 hour rhythm of gene programs regulating metabolism. How this is connected to diseases like Diabetes, you will get to know during the talk.