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Tonight our researchers shed some light on our complex and mysterious brains. What can virtual reality for animals teach us about brain function? And how could a map of the immune cells of the brain improve treatments for multiple sclerosis? Turn those brain cells on and find out!
What changes in the brain during inflammation?
Marta Joana Costa Jordão (Innate Immunity Group, Institute for Neuropathology Freiburg)
Did you need that our brain is protected by a fortress where different cells control what goes in and out of the brain? And that changes into these cells can often lead to disease? During Multiple Sclerosis the brain becomes under attack and immune cells at the brain barrier are believed to contribute to the onset of the disease. Which cells can be found at this barrier and how do they change during inflammation was still unknown. We now show that specialized immune cells promote the infiltration of harmful cells into the brain which leads to the development of the pathology.
Think before you swat: what we can learn from the fruit fly.
Andrew Straw (Professor at the Institute of Biology I)
Did you know that the fruit flies in your kitchen have been used to make countless important discoveries, including several that led to Nobel Prizes? For example, we wake up based on daily rhythms whose basis we share with these insects (Nobel Prize in Physiology or Medicine 2017). The shape of our body is genetically programmed during embryonic development also with the same rules as the fly (Nobel Prize in Physiology or Medicine 1995). Come hear about these important discoveries and how they were enabled by this humble and sometimes pesky animal.